منابع مشابه
Mutant enzymes challenge all assumptions
Enzymes called Rab GTPases that carry so-called "activating" mutations may never become activated at all.
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Key assumptions about bisphenol A (BPA) exposure and bioavail-ability may be off base, according to a new report in EHP that questions the traditional interpretation of biomonitoring data underlying current risk assessments of the chemical. Laboratory research suggests that BPA, a widely used chemical for polycarbonate plastics and other products, is an endocrine disruptor with potential advers...
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18. Stamnaes J, Dorum S, Fleckenstein B, Aeschlimann D, Sollid LM. Gluten T cell epitope targeting by TG3 and TG6; implications for dermatitis herpetiformis and gluten ataxia. Amino Acids. 2010;39:1183-1191. 19. Bushara KO, Shill H, Hallett M. Open label trial of gluten free diet in sporadic and hereditary cerebellar ataxia with gluten sensitivity. Mov Disord. 2002;17:S325. 20. Hadjivassiliou M...
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Lord Longford s Group, reporting only six months after being appointed, n' m numerous proposals for reform. Some of these, like the suggestions for strengthen^1 8 j police (e.g. by the codification of powers of arrest) are neither new nor very controvef j. The re-classification of offences, so as to give a truer picture of their nature and graV ^f already under official consideration. It is wid...
متن کاملMutant metabolic enzymes are at the origin of gliomas.
Mutations of the isocitrate dehydrogenase (IDH) metabolic enzymes IDH1 and IDH2 have been found to be frequent and early genetic alterations in astrocytomas and oligodendrogliomas. All mutations identified to date affect a single amino acid located within the isocitrate binding site (R132 of IDH1 and the analogous R172 residue of IDH2). IDH1 and IDH2 mutations define a specific subtype of gliom...
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ژورنال
عنوان ژورنال: eLife
سال: 2014
ISSN: 2050-084X
DOI: 10.7554/elife.02171